Blar i forfatter "Uzelac, Lidija"

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    • Azithromycin-liposomes as a novel approach for localized therapy of cervicovaginal bacterial infections 

      Vanic, Zeljka; Rukavina, Zora; Manner, Suvi; Fallarero, Adyary; Uzelac, Lidija; Kralj, Marijeta; Amidzic Klaric, Danijela; Bogdanov, Anita; Raffai, Timea; Virok, Deszo Peter; Filipovic-Grcic, Jelena; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-30)
      <p><i>Background - </i>Efficient localized cervicovaginal antibacterial therapy, enabling the delivery of antibiotic to the site of action at lower doses while escaping systemic drug effects and reducing the risk of developing microbial resistance, is attracting considerable attention. Liposomes have been shown to allow sustained drug release into vaginal mucosa and improve delivery of antibiotics ...

    • A Novel Approach for the Treatment of Aerobic Vaginitis: Azithromycin Liposomes-in-Chitosan Hydrogel 

      Cacic, Ana; Amidžic Klaric, Daniela; Keser, Sabina; Radikovic, Maja; Rukavina, Zora; Jøraholmen, May Wenche; Uzelac, Lidija; Kralj, Marijeta; Skalko-Basnet, Natasa; Segvic Klaric, Maja; Vanic, Zeljka (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-28)
      Biocompatible mucoadhesive formulations that enable a sustained drug delivery at the site of action, while exhibiting inherent antimicrobial activity, are of great importance for improved local therapy of vaginal infections. The aim of this research was to prepare and evaluate the potential of the several types of azithromycin (AZM)-liposomes (180–250 nm) incorporated into chitosan hydrogel (A ...